Alcoholic Beverages Have Different Effects on Lungs in Men and Women

Heavy and regular increased consumption of beer and liquors would cause an increased risk of lung cancer. Contrary to that a modest wine consumption is associated with a reduced risk for the lung cancer.

Chun Chao of the “Kaiser Permanenate Southern California in Pasadena “and his research team conducted this study. Results of meta-analysis after this study established the fact with sufficient experimental analyses and evidences. Findings of this study with detailed analysis have been published in the journal “Cancer Epidemiology Biomarkers and Prevention” recently.

All previously performed epidemiologic studies have indicated that beer, wine, and liquor may have different effects on the risk for lung cancer. Present study focused on the verification of all such previous claims.Chun Chao, from Kaiser Permanente Southern California in Pasadena, planned and conducted a comprehensive search of the ‘PubMed database’ to find studies that examined associations between alcohol consumption and lung cancer.

Subsequently the study planned for ten case-control studies included in the final analysis, resulting in a total of 4391 cases and 10,324 controls, along with four cohort studies. This comprehensive study therefore included a combined total of 453,751 participants. Approximately 4119 participants of these total participants developed lung cancer.

It was observed during this study that drinking beer once a day or more was directly related to an increased risk for lung cancer and the relative risk was 1.23 in comparison to those with no consumption.

Analysis of this typical association was seen in both men and women. The results were more significantly alarming only in men. The researchers also observed that the consumption of less than one drink of beer a day showed an inverse association with lung cancer and the relative risk was only 0.78.

Detailed analysis of the wine consumption data indicated that it was protective against lung cancer if the relative risk is below 0.77 among those who are consuming less than one drink every day in comparison to those participants who did not consume at all and those with a relative risk of 0.78 for those consuming one drink or more per day.

The study did not find any association between liquor drinking and lung cancer in women. However, in men with average liquor consumption of one drink or more per day were directly associated and linked to an increased risk for lung cancer at a relative risk of 1.33.

“Our results suggest that different types of alcoholic beverages may have different effects on lung carcinogenesis. However, the possibility that residual confounding may explain these associations cannot be excluded at this point“, said the study authors in the report.

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