According to the US researchers, normal cells can take cancer to new sites before the development of the tumor as they lay dormant until the activation of key genes.
The study has been published in the journal ‘Science’ and it gives details about why some breast cancers cause new tumors after the treatment of the disease.
Secondary or metastatic cancers become the cause of a large number of deaths in patients with breast cancer.
Specialists from UK explain that it’s quite important to know more about the spread of the disease.
Normally, it is believed that the cancer spreads to other parts in the body at the time of advancement of the disease and occurs as a late event in the body.
It is also believed that cancer cells remain dormant until they undergo some genetic alterations that make them more aggressive.
A researchers’ team from The Memorial Sloan-Kettering Center, New York, injected mice with normal breast tissue cells that were engineered so the scientists could activate cancer genes.
The researchers found that the cells could travel in the bloodstream to the other sites like lungs and survived there for more than 16 weeks and they didn’t express any onocgenes.
These cells didn’t become more aggressive in the lungs until the activation of the oncogenes.
The researchers say that if every step of the process is examined that is metastasizes by the cancer, it is possible to find the ways to destroy the cells that can cause disease to spread in the body.
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