SUNDAY, April 6 (HealthDay News) — A daily dose of pain killers like ibuprofen or acetaminophen shows to enhance muscle mass as well as strength among elderly men and women who do weight training.”It’s astonishing,” stated principal investigator Todd A. Trappe, an associate professor with the Human Performance Lab at Ball State University in Muncie, Ind.”But the issue is that there is still a long way to go and search pretty long and hard to find anything that would reveal the strong and positive effect on muscle growth that was observed. “
His team presented its research April 6 at the Experimental Biology annual meeting, in San Diego.
Muscle metabolism
The discovery prevents from an earlier study the team made on the short-term effects of ibuprofen and acetaminophen on muscle metabolism among young men and women who had been lifting weights over a 24-hour period.They noted a negative effect here, as the two drugs were found to have jammed the workings of an enzyme named as Cox and inhibited the addition of new protein to muscle.
“So we considered we required to look at this long-term and among older people, who were more likely to be taking these drugs continually for pain and other reasons, because we’re trying to tell them that they needed to be more active as they aged, yet there might be an intrusive effect,” Trappe stated.
To investigate the question, the researchers targeted 36 men and women between the ages of 60 and 78 who joined in a three-month agenda of knee-extensor weight training at the Human Performance Lab.
Training duration — 15- to 20-minute sessions three times per week — was set at a level known by the researchers to quicken noteworthy muscle mass and strength growth in a participant’s thigh muscles, without any medication.
Placebo
In addition, the participants were randomly divided into an acetaminophen group, an ibuprofen group or a placebo. The two drugs were consumed at suggested daily dosage levels, as noted on current over-the-counter packaging.
Muscle tissue samples
To the research team’s astonishment, an investigation of muscle tissue samples taken before and after showed that the ibuprofen group noticed a 7 percent growth in muscle mass and strength, those taking either acetaminophen or ibuprofen noticed even greater gain about 40 percent to 60 percent more.
Trappe conceived that the two drugs could caused the body to overcompensate for an early blocking of the enzyme any muscle needs to grow — quickening muscles to send fresh and influential signals requiring even more enzyme than the body would usually produce.In the meantime, David Bassett Jr., a professor of exercise science at the University of Tennessee in Knoxville, hailed the repute of the physiology lab that made the research and recommended the finding as “within the kingdom of believability.” However, Bassett stated that despite the obvious absence of serious side effects, only one study is not sufficient to conclude that ibuprofen and acetaminophen have such muscle gains benefits in actual.
Harms/benefits
“Apparently, there is no harm in taking them, but there also may be no benefit either,” he further added. “It’s still unclear, and it will be essential to confirm these findings with further research. But if it is so, it is potentially something that many people would like to try.”
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Hi there is a type in the story,
the paragraph starting with: To the research team’s astonishment, an investigation of muscle tissue samples taken before and after showed that the ibuprofen group noticed a 7 percent growth in muscle … I think the ibuprofen group shall be changed to placebo group.
Thanks
John Brodeur