Causes of Skin Cancers

The most common cause of skin cancers are ultraviolet (UV) rays, either from the sun, or from UV-emitting lamps, like those in tanning saloons. Both UV-A and UV-B rays may cause skin cancer.

Other possible causes of skin cancers include:

  • A high dose or repeated X-ray exposure (1,2)
  • Exposure to arsenic (pesticides, wood preservatives, miners, sheep shearers, farmers) (1), pitch (from distillation of wood or coal tar), creosote, or radium (5)
  • Therapy that destroys immune cells – chemotherapy, radiotherapy, immunosuppression in organ or bone marrow transplantation (2)
  • Smoking – increases risk of squamous cell carcinoma (4)

Risk Factors for Developing a Skin Cancer

The possibility of developing a skin cancer increases with the following factors:

  • People with fair skin, freckles, blond or red hair, blue or green eyes are at most risk to develop skin cancer (2).  
  • Skin disorders with lack of skin pigment melanin (albinism, xeroderma pigmentosum) (2)
  • Tanning poorly (1)
  • Several, unusual or big moles at birth (2)
  • New or changing mole (5)
  • Close relatives with skin cancer (2)
  • Previous skin cancer (2)
  • Severe sunburn, especially early in life (2)
  • Scars (2)
  • Actinic keratosis (1)
  • HIV infection - increases risk of Kaposis’s sarkoma (3)
  • A constant exposure to the UV rays: a high altitude, regions close to equator and regions with impaired ozone layer in atmosphere (Australia) (1)
  • Repeated sun exposure (outdoor workers, sailors, farmers, drivers) (1)
  • White race, men, age after 50 (6

Related Articles:

References:

  1. Skin cancer causes and risk factors  (rush.edu)
  2. Skin cancer causes and risk factors  ( emedicinehealth.com)
  3. Skin cancer causes and risk factors  (umm.edu)
  4. Smoking increases risk for squamous cell carcinoma  (cancer.org)
  5. Radium increases risk of skin carcinoma  (cancer.org)
  6. White men after 50 have increased risk for skin cancer  (skincancer.org)

Article reviewed by Dr. Greg. Last updated on April 12, 2011