Types of Antifungals
Antifungal drugs can be divided broadly into medications for systemic and superficial fungal infections. Systemic drugs are used for deeper lying infections which can only be reached by drugs traveling in the bloodstream. There is no specific site that is targeted but rather the distribution is essentially through the whole body. Drugs for systemic (deep) fungal infections include :
- Amphotericin B
Drugs for superficial fungal infections include both oral and topical medication. These drugs are mainly developed for fungal infections of the skin and the tissue just underneath it (subcutaneous). Oral drugs are mainly in the form of tablets and capsules that are taken through the mouth, travel through the bloodstream and reach the skin to target these infections. Topical applications include creams, ointments, lotions and gels.
- Oral medications include drugs such as terbinafine and griseofulvin.
- Topical medications include nystatin, topical azoles, topical allylamines and other topical drugs.