Deficiency of the vitamin D in the body could be the result of an abnormal metabolism of the vitamins. This deficiency of the Vitamin D associated with active tuberculosis (TB) is not explained by dietary or sun exposure factors.
Epidemiologic evidence suggested by the British research team established a link between vitamin D deficiency and TB, possibly owing to an immuno-modulatory role for vitamin D. Findings of this research ahs been published in the recent edition of the journal “Thorax”.
Dr.Heather Milburn from the ‘Guy’s Hospital, London’ and colleague researchers measured serum vitamin D levels at presentation and throughout the treatment in a mixed ethnic group of 178 patients attending an inner London chest clinic for possible TB and 130 healthy individuals they had contact with. Researchers were trying to find out the relationship between factors like seasonality, ethnic differences, and association with active disease.
Researchers found out that both diet and sunlight exposures are particularly important factors influencing serum vitamin D concentrations. They also administered dietary and sun exposure level with the help of questionnaires given to 35 patients and 35 healthy control individuals. Responses from all these individuals were matched for age, gender, and skin color.
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