Dracunculiasis is a nematode (parasitic worm) infection caused by the guinea worm, Dracunculus medinensis. It is also known as guinea worm disease (GWD). It has become a very rare infection due to various eradication campaigns globally over the past quarter of a century. Dracunculiasis may be eradicated completely in years to come. The worm enters the gut through contaminated water and then migrates to the skin once it matures. A guinea worm infection is rarely serious to the point where it causes major debility or death. However, bacterial infections may arise at the site where the worm erupts from the skin. In rare cases, the bacterial infection can complicate to the point of sepsis which may be life-threatening.